Colgate® Total® significantly reduces inflammation in patients with peri-implant mucositis vs. ordinary fluoride toothpaste.
135 male and female adults with established plaque and gingivitis in Bangkok, Thailand. All 135 subjects completed the study.
A recent randomized, double-blind, parallel-group clinical study performed on 135 male and female subjects with established plaque, compared the efficacy of a triclosan/copolymer toothpaste in reducing plaque and gingivitis with a herbal sodium bicarbonate toothpaste, and a negative control: non-antibacterial fluoride toothpaste with sodium fluoride. Participants with established plaque and gingivitis were given oral hygiene instructions and were randomly assigned to one of the 3 study groups. Following baseline examination, subjects were instructed to brush twice per day with their assigned toothpaste and toothbrush for one minute. After 3 months and 6 months of product use, subjects returned to the testing facility for their follow-up examinations.
Colgate® Total Pro-Gum Health toothpaste, with 0.3 % triclosan, 2.0 % copolymer and 1450 ppm fluoride, provided statistically significantly superior efficacy in reducing plaque and gingivitis at 3 months and 6 months, compared with a toothpaste with a proprietary blend of herbal extracts, sodium bicarbonate and 1400 ppm fluoride, as well as a negative control dentifrice with 1450 ppm fluoride alone. There were no significant differences between the herbal sodium bicarbonate toothpaste and the negative control toothpaste at either time point, for either plaque or gingivitis.
Full Study Title:
Colgate® Total Pro Gum Health Toothpaste delivers superior efficacy against plaque and gingivitis compared with herbal fluoride bicarbonate toothpaste.
Triratana T., et al. J Dent Res. 2014, 94 (Spec Iss A): 1632